ANTICANCER VACCINE COMPOSITION CONTAINING PEPTIDE WT1 FOR TRANSDERMAL ADMINISTRATION Russian patent published in 2019 - IPC A61K38/10 A61K39/00 A61K31/45 A61K31/437 A61K31/451 A61K31/513 A61K31/739 A61K9/00 

Abstract RU 2685933 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a composition of an anticancer vaccine for transdermal administration for use in inducing cell-mediated immunity, where cancer overexpresses WT1. Said composition contains an effective amount of peptide WT1 and/or modified peptide WT1, selected from a group consisting of peptide Db126, peptide RYF and peptide AYL. Also, said composition contains an effective amount of a first stimulator of induction of cellular immunity, which is a pharmacologically acceptable acid or pharmacologically acceptable salt thereof, where the acid is selected from a group consisting of isostearic acid, decanoic acid, myristic acid and malic acid.

EFFECT: invention enables efficient induction of cell-mediated immunity against cancer.

9 cl, 2 dwg, 7 tbl

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RU 2 685 933 C2

Authors

Okubo Katsuyuki

Maeda Josiki

Okadzaki Arimiti

Asari Dajsuke

Sisido Takuya

Khori Mitsukhiko

Sugiyama Kharuo

Dates

2019-04-23Published

2014-01-29Filed