FIELD: biotechnology.
SUBSTANCE: invention relates to a composition of an anticancer vaccine for transdermal administration for use in inducing cell-mediated immunity, where cancer overexpresses WT1. Said composition contains an effective amount of peptide WT1 and/or modified peptide WT1, selected from a group consisting of peptide Db126, peptide RYF and peptide AYL. Also, said composition contains an effective amount of a first stimulator of induction of cellular immunity, which is a pharmacologically acceptable acid or pharmacologically acceptable salt thereof, where the acid is selected from a group consisting of isostearic acid, decanoic acid, myristic acid and malic acid.
EFFECT: invention enables efficient induction of cell-mediated immunity against cancer.
9 cl, 2 dwg, 7 tbl
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Authors
Dates
2019-04-23—Published
2014-01-29—Filed