ANTICANCER VACCINE COMPOSITION CONTAINING WT1 PEPTIDE FOR TRANSDERMAL ADMINISTRATION Russian patent published in 2019 - IPC A61K39/00 A61K38/10 A61K9/00 

Abstract RU 2687144 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a composition of an anticancer vaccine for transdermal administration for use in inducing cellular immunity against cancer with overexpression of the WT1 gene. Above composition contains an effective amount of: Db126 peptide and a cyclooxygenase inhibitor selected from a group consisting of ethodolac, loxoprofen and/or a salt thereof, indometacin, aspirin, diclofenac, ketoprofen, celecoxib and valdecoxib.

EFFECT: invention enables efficient induction of cell-mediated immunity against cancer.

5 cl, 9 dwg, 8 tbl

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RU 2 687 144 C2

Authors

Okubo Katsuyuki

Maeda Josiki

Okadzaki Arimiti

Asari Dajsuke

Sisido Takuya

Khori Mitsukhiko

Sugiyama Kharuo

Dates

2019-05-07Published

2014-01-29Filed