FIELD: biotechnology.
SUBSTANCE: invention relates to a composition of an anticancer vaccine for transdermal administration for use in inducing cellular immunity against cancer with overexpression of the WT1 gene. Above composition contains an effective amount of: Db126 peptide and a cyclooxygenase inhibitor selected from a group consisting of ethodolac, loxoprofen and/or a salt thereof, indometacin, aspirin, diclofenac, ketoprofen, celecoxib and valdecoxib.
EFFECT: invention enables efficient induction of cell-mediated immunity against cancer.
5 cl, 9 dwg, 8 tbl
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Authors
Dates
2019-05-07—Published
2014-01-29—Filed