FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and aims at treating, preventing or relieving a disease or a condition which is to be treated, prevented or relieved by NMDA receptor inhibition. The method involves administering a total daily dose of approximately 2 to approximately 50 mg of a compound of formula
or a pharmaceutically acceptable salt thereof into the patient in need thereof. What is also declared is using the compound of formula (I) or a pharmaceutically acceptable salt thereof for treating, preventing or relieving the course of a cognitive disorders, a neurodegenerative disorder, pain, depression, attention deficient hyperactivity disorder or an addiction, and for treating, preventing or relieving the course of a disease or a disorder by inhibition of NMDA receptors containing an NR2B subunit wherein a total daily dose of the compound makes from approximately 2 to approximately 50 mg.
EFFECT: group of the inventions is high effective in treating, preventing or relieving the course of a disease or a disorder which is to be treated, prevented or relieved by NMDA receptor inhibition.
10 cl, 6 dwg, 3 ex
Title | Year | Author | Number |
---|---|---|---|
HETEROAROMATIC NMDA RECEPTOR MODULATORS AND THEIR USE | 2019 |
|
RU2800064C2 |
CYCLOPROPYLPIPERIDINE GLYCINE TRANSPORTER INHIBITORS | 2005 |
|
RU2387644C2 |
MEMANTINE THERAPY FOR ALZHEIMER'S DISEASE OF LOW AND LOW TO MODERATE SEVERITY | 2005 |
|
RU2371173C2 |
3-FLUOROPIPERIDINES AS NMDA/NR2B ANTAGONISTS | 2004 |
|
RU2339630C2 |
COMPOSITIONS AND METHODS ASSOCIATED THEREWITH | 2017 |
|
RU2764716C2 |
COMBINATIONS OF COMPOUNDS MODULATING THE NMDA RECEPTOR | 2015 |
|
RU2721948C2 |
3,3-DIFLUOROPIPERIDINE CARBAMATE HETEROCYCLIC COMPOUNDS AS NR2B NMDA RECEPTOR ANTAGONISTS | 2016 |
|
RU2735277C2 |
PEPTIDE ANTAGONIST OF THE NMDA RECEPTOR | 2019 |
|
RU2716258C1 |
METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA WITH USING NEUROLEPTIC COMBINED THERAPY | 2007 |
|
RU2508096C2 |
TARGET DRUG WITH NEW COMPOSITIONS, COMBINATIONS AND METHODS | 2018 |
|
RU2760558C2 |
Authors
Dates
2013-11-27—Published
2009-03-26—Filed