FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a chemical compound of formula (II), as well as to pharmaceutical compositions containing a chemical compound of formula (II), and to methods of treating various diseases and disorders, associated with NR2B antagonism, e.g. diseases and CNS disorders, such as depression, by administering a chemical compound of formula (II).
EFFECT: in this invention 3,3-difluoropiperidine carbamate heterocyclic compounds are proposed as NR2B NMDA receptor antagonists.
7 cl, 51 ex, 10 tbl, 11 dwg
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Authors
Dates
2020-10-29—Published
2016-05-31—Filed