FIELD: medicine.
SUBSTANCE: renoparenchymatous arterial hypertension is simulated in mature male rats by a chemical injury of the renal parenchyma by administering 4% paraformaldehyde 0.1 ml into an upper pole of both kidneys.
EFFECT: method provides obtaining the permanent blood pressure increase in a short period of time, high reproducibility, simplicity of the procedure, low invasiveness, short rehabilitation period in the formation of significant morphological and biochemical transformations in the target organs similar to the clinical versions of renoparenchymatous arterial hypertension.
2 tbl, 4 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF SIMULATING ATHEROSCLEROSIS | 2012 |
|
RU2500041C1 |
| PHARMACEUTICAL COMPOSITION INCLUDING RENIN INHIBITOR, CALCIUM CHANNEL BLOCKER AND DIURETIC | 2003 |
|
RU2316318C2 |
| APPLICATION OF ORGANIC COMPOUNDS | 2005 |
|
RU2426532C2 |
| METHOD OF RAT'S CARDIOVASORENAL ARTERIAL HYPERTENSION MODELLING | 2006 |
|
RU2327228C1 |
| METHOD OF SIMULATING MULTIPLE ORGAN PATHOLOGY IN RATS | 2011 |
|
RU2453002C1 |
| METHOD FOR SIMULATING MINERAL AND BONE DISORDERS IN CHRONIC KIDNEY DISEASE IN LABORATORY RATS | 2023 |
|
RU2822405C1 |
| METHOD OF SIMULATING ARTERIAL HYPERTENSION | 0 |
|
SU1645987A1 |
| TREATING NEPHROGENIC ARTERIAL HYPERTENSION ACCOMPANYING INCOMPLETE DUPLEX KIDNEY | 2014 |
|
RU2558467C1 |
| METHOD OF DIAGNOSIS OF CHRONIC PYELONEPHRITIS LATENT FORM IN PATIENTS WITH HYPERTENSIVE SYNDROME WITHOUT CONCOMITANT UROLOGICAL DISEASES | 1993 |
|
RU2079129C1 |
| METHOD OF DIAGNOSTICS OF VARIANTS OF ACUTE ISCHEMIC DAMAGE TO THE PANCREAS IN CASE OF ACUTE CARDIOVASCULAR INEFFICIENCY WITH IMPAIRED MICROCIRCULATORY BLOOD FLOW AND CENTRALIZATION OF BLOOD CIRCULATION OF VARIOUS ETHIO-PATHOGENETIC NATURE | 2018 |
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RU2681264C1 |
