FIELD: medicine.
SUBSTANCE: substance of the declared method consists in determining the genotypes and alleles of polymorphous variants of folate metabolism genes MTHFR C677T and A1298C, MTRR G66A by polymerase chain DNA synthesis with restriction analysis: If observing a combination of the allele T of the MTHFR C677T promoter polymorphism, the allele C of the MTHFR A1298C promoter polymorphism, the allele A of the MTRR G66A promoter polymorphism, the development of food intolerance is predicted in children.
EFFECT: using the method enables planning the preventive measures and therapeutic approach to an infant, ensures preventing the development of food-related aggravations and complications, and providing the maximum improvement of quality of life and working ability.
3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING FOOD ALLERGY TO COW MILK PROTEIN IN CHILDREN | 2020 |
|
RU2750353C1 |
| METHOD OF PREDICTING HIGH RISK OF REPRODUCTIVE LOSS IN FIRST TRIMESTER OF PREGNANCY | 2016 |
|
RU2611358C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING DISEASES ASSOCIATED WITH LEVEL OF IMMUNOGLOBULIN E (IGE) IN HUMAN BLOOD SERUM | 2019 |
|
RU2723390C1 |
| APPLICATION OF DNA-DIAGNOSTICS FOR PRESENCE OF POLYMORPHISM R353Q IN GENE OF FACTOR VII OF BLOOD COAGULATION FOR ESTIMATION OF PREDISPOSITION TO DEVELOPMENT OF HABITUAL NONCARRYING OF PREGNANCY AND METHOD OF PREDISPOSITION ESTIMATION TO THIS DISEASE BY MEANS OF ANALYSIS OF COMBINATION OF POLYMORPHISMS C677T OF GENE MTHFR AND OF GENE R353Q OF FACTOR VII | 2006 |
|
RU2330071C1 |
| METHOD FOR DETECTING EARLY PHYSIOLOGICAL CARDIAC MALFUNCTION IN CHILDREN IN CONDITIONS OF CONTAMINATION WITH PHENOL | 2017 |
|
RU2657821C1 |
| METHOD FOR PREDICTION OF EMBRYO ANEUPLOIDY IN THE EXTRACORPORAL FERTILIZATION PROGRAM IN WOMEN WITH ENDOMETRIOSIS-ASSOCIATED INFERTILITY | 2020 |
|
RU2752783C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING PROTHROMBOTIC CHANGES IN ADOLESCENTS WITH ESSENTIAL ARTERIAL HYPERTENSION | 2013 |
|
RU2514887C1 |
| METHOD OF PREDICTING DEVELOPMENT OF MULTIFACTOR PATHOLOGY IN CHILDREN BORN WITH APPLICATION OF AUXILIARY REPRODUCTIVE TECHNOLOGIES | 2011 |
|
RU2456911C1 |
| METHOD OF DIAGNOSTICS OF GENETIC DISORDERS IN PATHOLOGY OF HUMAN REPRODUCTION PROCESS | 2017 |
|
RU2665827C1 |
| METHOD FOR PREDICTION OF CLINICAL COURSE OF HAEMOPHILIA WITH LEVEL OF ACTIVITY FACTORS VIII, IX | 2019 |
|
RU2698453C1 |
