METHOD FOR DETECTING EARLY PHYSIOLOGICAL CARDIAC MALFUNCTION IN CHILDREN IN CONDITIONS OF CONTAMINATION WITH PHENOL Russian patent published in 2018 - IPC G01N33/49 

Abstract RU 2657821 C1

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine and biology. Method for detecting early physiological cardiac malfunction in children with phenol contamination includes the taking blood samples from the child and the determination of the phenol content in the sample, taking a sample of the buccal epithelium and isolation from this sample of deoxyribonucleic acid (DNA), genotyping of polymorphism of MTHFR and SULTIAI genes, studying of genotypes of the gene MTHFR C677T (rs1801133) and gene SULTIAI G2663A (rs9282861), while simultaneously meeting the following conditions: presence of variant homozygous or heterozygous genotypes of the gene MTHFR C677T (rs1801133) and gene SULTIAI G2663A (rs9282861), and if the concentration of phenol in the blood exceeds the background level by more than 1.5 times, the child is diagnosed with early physiological cardiac malfunction in the form of functional cardiopathy associated with contamination with phenol.

EFFECT: method is proposed for detecting early physiological cardiac malfunction in children.

1 cl, 1 tbl

Similar patents RU2657821C1

Title Year Author Number
METHOD FOR DETECTING PREDISPOSITION TO THE DEVELOPMENT OF METABOLIC SYNDROME IN THE FORM OF OBESITY IN SCHOOLCHILDREN AGED 7-10 YEARS 2022
  • Dolgikh Oleg Vladimirovich
  • Kazakova Olga Alekseevna
  • Mazunina Alena Aleksandrovna
  • Alikina Inga Nikolaevna
  • Nikonoshina Natalya Alekseevna
  • Starkova Kseniya Gennadevna
RU2779085C1
METHOD OF ESTIMATION OF INFLUENCE OF NITROSAMINES ON APOPTOSIS IN CHILDREN LIVING IN ADVERSE ENVIRONMENTAL CONDITIONS 2016
  • Dolgikh Oleg Vladimirovich
  • Zajtseva Nina Vladimirovna
  • Krivtsov Aleksandr Vladimirovich
  • Bubnova Olga Alekseevna
  • Dianova Dina Gumyarovna
  • Otavina Elena Alekseevna
  • Bezruchenko Nadezhda Vladimirovna
  • Perminova Irina Vladimirovna
RU2626516C1
METHOD FOR DETERMINING PREDISPOSITION TO DEVELOPING OBESITY IN CHILDREN IN CONDITIONS OF EXCESSIVE CONTAMINATION WITH ALUMINUM 2019
  • Dolgikh Oleg Vladimirovich
  • Zajtseva Nina Vladimirovna
  • Alikina Inga Nikolaevna
  • Krivtsov Aleksandr Vladimirovich
  • Guselnikov Maksim Anatolevich
  • Mazunina Alena Aleksandrovna
  • Nikonoshina Natalya Alekseevna
  • Chelakova Yuliya Aleksandrovna
  • Kazakova Olga Alekseevna
  • Vdovina Nadezhda Alekseevna
  • Kolegova Anastasiya Alekseevna
RU2700565C1
METHOD FOR EVALUATION OF STRONTIUM IMPACT ON APOPTOSIS, ASSOCIATED WITH ALLELLIC VARIANTS OF FAS GENE IN CHILDREN 2016
  • Dolgikh Oleg Vladimirovich
  • Zajtseva Nina Vladimirovna
  • Krivtsov Aleksandr Vladimirovich
  • Bubnova Olga Alekseevna
  • Dianova Dina Gumyarovna
  • Starkova Kseniya Gennadevna
  • Otavina Elena Alekseevna
  • Bezruchenko Nadezhda Vladimirovna
  • Legostaeva Tatyana Andreevna
  • Perminova Irina Vladimirovna
RU2621155C1
METHOD FOR DIAGNOSING DISORDERS OF THE AUTONOMIC NERVOUS SYSTEM IN GIRLS OF PRESCHOOL AGE ASSOCIATED WITH EXCESSIVE CONTAMINATION OF BIOLOGICAL MEDIA IN CHILDREN WITH MANGANESE 2021
  • Dolgikh Oleg Vladimirovich
  • Kazakova Olga Alekseevna
  • Mazunina Alena Aleksandrovna
  • Chelakova Yuliya Aleksandrovna
  • Alikina Inga Nikolaevna
  • Shirinkina Alisa Sergeevna
RU2773830C1
METHOD OF DETECTING DISORDERS OF PHYSIOLOGICAL IMMUNOSUPPRESSION IN CHILDREN IN FIRST GENERATION THROUGH PARENTAL LINEAGE WITH HEREDITARY TAINTED IN CONDITIONS OF ALUMINUM EXCESSIVE EXPOSURE 2017
  • Dolgikh Oleg Vladimirovich
  • Zajtseva Nina Vladimirovna
  • Krivtsov Aleksandr Vladimirovich
  • Bubnova Olga Alekseevna
  • Dianova Dina Gumyarovna
  • Otavina Elena Alekseevna
  • Bezruchenko Nadezhda Vladimirovna
  • Guselnikov Maksim Anatolevich
  • Perminova Irina Vladimirovna
  • Mazunina Alena Aleksandrovna
  • Nikonoshina Natalya Alekseevna
RU2655658C1
METHOD FOR DIAGNOSING EARLY MANIFESTATIONS OF BILIARY DYSKINESIA IN CHILDREN UNDER CONDITIONS OF BENZENE CONTAMINATION 2024
  • Zaitseva Nina Vladimirovna
  • Dolgikh Oleg Vladimirovich
  • Kazakova Olga Alekseevna
  • Ganich Tatiana Sergeevna
  • Iaroma Alesia Viacheslavovna
  • Otavina Elena Alekseevna
  • Alikina Inga Nikolaevna
RU2821553C1
DIAGNOSTIC TECHNIQUE FOR EARLY MANIFESTATIONS OF RESPIRATORY ALLERGOSIS IN CHILDREN IN CONDITIONS OF EXCESSIVE CONTAMINATION WITH ALUMINUM 2018
  • Dolgikh Oleg Vladimirovich
  • Zajtseva Nina Vladimirovna
  • Alikina Inga Nikolaevna
  • Krivtsov Aleksandr Vladimirovich
  • Guselnikov Maksim Anatolevich
  • Mazunina Alena Aleksandrovna
  • Nikonoshina Natalya Alekseevna
  • Chelakova Yuliya Aleksandrovna
  • Mukhacheva Elena Aleksandrovna
RU2693471C1
METHOD FOR ESTABLISHING A PREDISPOSITION IN THE FORMATION OF POLAR STRESS SYNDROME IN STUDENTS AGED 7-13 YEARS LIVING IN THE POLAR REGIONS 2022
  • Dolgikh Oleg Vladimirovich
  • Kazakova Olga Alekseevna
  • Mazunina Alena Aleksandrovna
  • Alikina Inga Nikolaevna
  • Chelakova Yuliya Aleksandrovna
  • Vdovina Nadezhda Alekseevna
  • Nikonoshina Natalya Alekseevna
RU2793062C1
METHOD FOR PREDICTION OF MEN'S RISK OF ESSENTIAL HYPERTENSION ASSOCIATED WITH OBESITY 2018
  • Dolgikh Oleg Vladimirovich
  • Zajtseva Nina Vladimirovna
  • Alikina Inga Nikolaevna
  • Krivtsov Aleksandr Vladimirovich
  • Guselnikov Maksim Anatolevich
  • Mazunina Alena Aleksandrovna
  • Nikonoshina Natalya Alekseevna
  • Chelakova Yuliya Aleksandrovna
  • Mukhacheva Elena Aleksandrovna
  • Vdovina Nadezhda Alekseevna
RU2693469C1

RU 2 657 821 C1

Authors

Dolgikh Oleg Vladimirovich

Zajtseva Nina Vladimirovna

Krivtsov Aleksandr Vladimirovich

Kazakova Olga Alekseevna

Dianova Dina Gumyarovna

Otavina Elena Alekseevna

Bezruchenko Nadezhda Vladimirovna

Guselnikov Maksim Anatolevich

Perminova Irina Vladimirovna

Mazunina Alena Aleksandrovna

Nikonoshina Natalya Alekseevna

Legostaeva Tatyana Andreevna

Dates

2018-06-15Published

2017-10-05Filed