FIELD: chemistry.
SUBSTANCE: invention relates to a method for synthesis of novel 4-(1H-indol-3-yl)-but-3-en-2-one derivatives of general formula 3: , : which can be used in synthesis of novel preparations for pharmaceutical and agricultural purposes. The method involves mixing 2-alkyl-5-(2-amino-4-alkylphenyl)-furans 1 with aromatic and heteroaromatic aldehydes 2 in acetic acid in equimola ratio at temperature 35°C for 40 minutes in the presence of 0.01 ml hydrochloric acid.
EFFECT: improved method.
2 tbl, 5 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD PRODUCING 4-{1-[(4-METHYLPHENYL)SULPHONYL]-1H-INDOL-2-YL}BUT-3-EN-2-ONE DERIVATIVES | 2012 |
|
RU2488581C1 |
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METHOD OF PRODUCING (E)-4-(6,7-DIMETHOXY-2-METHYL-3-QUINOLYL)-3-BUTEN-2-ONE DERIVATIVES | 2010 |
|
RU2425034C1 |
METHOD OF PRODUCING BIS(5-ALKYL-2-FURYL)(2-AZIDOPHENYL)METHANE DERIVATIVES | 2012 |
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PRODRUG FORMING COMPOUNDS | 2014 |
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RU2667942C2 |
Authors
Dates
2011-01-20—Published
2009-07-21—Filed