METHOD FOR SYNTHESIS OF 4-(1H-INDOL-3-YL)-BUT-3-EN-2-ONE DERIVATIVES Russian patent published in 2011 - IPC C07D209/12 C07D405/04 C07D409/04 

Abstract RU 2409564 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method for synthesis of novel 4-(1H-indol-3-yl)-but-3-en-2-one derivatives of general formula 3: , : which can be used in synthesis of novel preparations for pharmaceutical and agricultural purposes. The method involves mixing 2-alkyl-5-(2-amino-4-alkylphenyl)-furans 1 with aromatic and heteroaromatic aldehydes 2 in acetic acid in equimola ratio at temperature 35°C for 40 minutes in the presence of 0.01 ml hydrochloric acid.

EFFECT: improved method.

2 tbl, 5 ex

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RU 2 409 564 C1

Authors

Butin Aleksandr Valerianovich

Pilipenko Arkadij Sergeevich

Uchuskin Maksim Grigor'Evich

Dates

2011-01-20Published

2009-07-21Filed