FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents a method for direct transmucosal buprenorphine delivery into an individual's body as an analgesic, involving coating an individual's oral mucosa with a biodegradable drug delivery agent containing buprenorphine in a buffer mucoadhesive polymer diffuse medium characterised by a pH value within the range of 4 to 6 and related to a barrier medium to form a one-direction gradient when coating the mucosa with the delivery agent and delivering buprenorphine into the individual body.
EFFECT: invention provides the improved delivery profile and more effective drug delivery.
47 cl, 4 ex, 4 tbl, 6 dwg
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