SET OF DIFFERENTIATING AND SPECIFIC OLIGONUCLEOTIDES FOR IDENTIFYING DNA OF ACUTE INTESTINAL INFECTION AGENTS, METHOD OF IDENTIFYING ACUTE INTESTINAL INFECTION, MICROCHIP AND DIAGNOSTIC SYSTEM FOR CARRYING OUT METHOD Russian patent published in 2014 - IPC C12N15/11 C12Q1/68 

Abstract RU 2509804 C2

FIELD: chemistry.

SUBSTANCE: invention relates to molecular biology and can be used in diagnostic studies aimed at detecting acute intestinal infection (AII) agents. Disclosed is a set of differentiating oligonucleotides (probes), which enables to determine, in a biological sample, DNA of pathogenic microorganisms which cause AII, and specific identification thereof, where said microorganisms relate to a group which includes Shigella spp. and Enteroinvasive E.coli (EIEC), Salmonella spp., Campylobacter Jejuni, Proteus mirabilis, Klebsiella pneumoniae.

EFFECT: described is design of a biochip on which is immobilised a set of probes disclosed herein, designed to perform rapid analysis of AII agents in clinical samples and material obtained from environmental media.

2 cl, 4 tbl, 2 dwg, 5 ex

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RU 2 509 804 C2

Authors

Granovskij Igor' Ehduardovich

Ajvazjan Sona Robertovna

Prusakova Ol'Ga Vadimovna

Afanas'Eva Gajda Vladislavovna

Malov Valerij Anatol'Evich

Beletskij Igor' Petrovich

Dates

2014-03-20Published

2010-03-31Filed