BIOLOGICAL MICROCHIP WITH PRIMER SET FOR ANALYSIS OF POLYMORPHISM IN AB0, HLA-DQA1, AMEL, DARC, NAT2 GENES Russian patent published in 2016 - IPC C12N15/00 C12Q1/68 

Abstract RU 2582216 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry. Disclosed is set of differentiating oligonucleotides for analysis of polymorphism in genes AB0, HLA-DQA1, AMEL, DARC, NAT2 using hydrogel DNA-microchips (biochips). Biochip enables detecting nucleotide composition in fourteen polymorphous positions that in turn enables to establish genotype in said genes. Also disclosed is set of PCR primers for amplifying said loci.

EFFECT: invention increases discriminatory potential of biochip (36,450 genotype groups).

3 cl, 3 dwg, 3 tbl, 4 ex

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RU 2 582 216 C2

Authors

Fesenko Denis Olegovich

Kornienko Aleksandra Evgenevna

Nasedkina Tatjana Vasilevna

Zasedatelev Aleksandr Sergeevich

Dates

2016-04-20Published

2014-03-13Filed