FIELD: medicine.
SUBSTANCE: proposed group of inventions relates to medicine. Proposed are method and a set of oligonucleotide probes for the determination of polymorphic markers in the genes of the metabolism of drugs and the immune response genes.
EFFECT: proposed group of inventions makes it possible to determine terminal mutations in genes involved in the metabolism of essential drugs in the acute leukemia treatment in children and in the immune response genes.
4 cl, 2 dwg, 3 tbl, 4 ex
Title |
Year |
Author |
Number |
METHOD OF ANALYZING POLYMORPHIC MARKERS IN THE GENES VKORC1, CYP4F2, CYP2C9, CYP2C19, ABCB1, ITGB3 TO DETERMINE INDIVIDUAL SENSITIVITY TO ANTICOAGULANT DRUGS |
2018 |
- Ikonnikova Anna Yurevna
- Nasedkina Tatyana Vasilevna
- Zasedatelev Aleksandr Sergeevich
|
RU2689400C1 |
METHOD OF DETERMINING POLYMORPHIC MARKERS IN CYP2C19 AND CYP2D6 GENES FOR DETERMINING INDIVIDUAL SENSITIVITY TO ANTIDEPRESSANTS |
2018 |
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- Pozhitnova Viktoriya Olegovna
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- Zasedatelev Aleksandr Sergeevich
|
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METHOD FOR DETERMINING POLYMORPHIC MARKERS IN SLCO1B1, APOE AND ABCB1 GENES FOR DETERMINING INDIVIDUAL SENSITIVITY TO STATINS |
2018 |
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- Nasedkina Tatyana Vasilevna
- Zasedatelev Aleksandr Sergeevich
|
RU2695783C1 |
METHOD FOR ANALYSIS OF GENETIC POLYMORPHYSM, DEFINING PREDISPOSITION TO TUMOR DISEASES AND INDIVIDUAL SENSITIVITY TO PHARMACEUTICAL AGENTS BY USING OLYGONUCLEOTIDE BIOLOGICAL MICROARRAY (BIOARRAY) |
2005 |
- Zasedatelev Aleksandr Sergeevich
- Nasedkina Tat'Jana Vasil'Evna
- Glotov Andrej Sergeevich
|
RU2303634C2 |
METHOD OF IDENTIFYING RNA OF INFLUENZA VIRUSES A AND B WITH SIMULTANEOUS DETERMINATION OF VARIANTS OF HEMAGGLUTININ AND NEURAMINIDASE OF INFLUENZA VIRUS A, IDENTIFICATION OF GENETIC MARKERS OF PATHOGENICITY AND RESISTANCE TO INFLUENZA PREPARATIONS ON BIOLOGICAL MICROCHIPS, BIOCHIP, SET OF OLIGONUCLEOTIDE PROBES, USED IN METHOD |
2015 |
- Gejdarov Rustam Nuraddin Ogly
- Fesenko Evgenij Evgenevich
- Mikhajlovich Vladimir Mikhajlovich
- Dementeva Ekaterina Igorevna
- Zasedatelev Aleksandr Sergeevich
- Shaskolskij Boris Leonidovich
- Kiselev Oleg Ivanovich
|
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METHOD FOR IDENTIFYING MUTATIONS IN THE GENE OF PENICILLIN-BINDING PROTEIN 2 PENA NEISSERIA GONORRHOEAE, LEADING TO RESISTANCE TO BETA-LACTAM ANTIBIOTICS, ON BIOLOGICAL MICROCHIPS |
2020 |
- Gryadunov Dmitrij Aleksandrovich
- Dementeva Ekaterina Igorevna
- Kandinov Ilya Denisovich
- Kravtsov Dmitrij Vitalevich
- Shaskolskij Boris Leonidovich
- Chestkov Aleksandr Viktorovich
- Solomka Viktoriya Sergeevna
- Kubanov Aleksej Alekseevich
|
RU2741099C1 |
BIOLOGICAL MICROCHIP WITH PRIMER SET FOR ANALYSIS OF POLYMORPHISM IN AB0, HLA-DQA1, AMEL, DARC, NAT2 GENES |
2014 |
- Fesenko Denis Olegovich
- Kornienko Aleksandra Evgenevna
- Nasedkina Tatjana Vasilevna
- Zasedatelev Aleksandr Sergeevich
|
RU2582216C2 |
METHOD FOR IDENTIFICATION OF GENETIC POLYMORPHISMS AFFECTING METABOLISM OF ANTICANCER DRUGS USING BIOLOGICAL MICROCHIPS |
2018 |
- Gejdarov Rustam Nuraddin Ogly
- Mikhajlovich Vladimir Mikhajlovich
- Popov Anatolij Yurevich
- Titov Sergej Vladimirovich
- Emelyanova Marina Aleksandrovna
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|
RU2697096C1 |
METHOD OF ANALYSIS OF SOMATIC MUTATIONS IN THE BCR/ABL CHIMERIC GENE USING RT-PCR AND SUBSEQUENT HYBRIDIZATION WITH OLIGONUCLEOTIDE BIOLOGICAL MICROCHIP (BIOCHIP) |
2015 |
- Ikonnikova Anna Yurevna
- Nasedkina Tatyana Vasilevna
- Zasedatelev Aleksandr Sergeevich
|
RU2609641C1 |
SET OF OLIGONUCLEOTIDE PRIMERS AND PROBES FOR GENETIC TYPING OF POLYMORPHOUS DNA LOCI ASSOCIATED WITH A RISK OF PROGRESSION OF SPORADIC FORM OF ALZHEIMER'S DISEASE IN RUSSIAN POPULATIONS |
2014 |
- Nasedkina Tatyana Vasilevna
- Gra Olga Alekseevna
- Nizamutdinov Igor Igorevich
- Zasedatelev Aleksandr Sergeevich
|
RU2600874C2 |