FIELD: medicine.
SUBSTANCE: the present innovation deals with hybridization of chimeric amplified fluorescently labeled product consisted of gene sequences that participate in certain chromosomal leucosis-associated translocation with oligonucleotide microchip. The method deals with reverse transcription, two-stage "socket" multiplex PCR; labeling chimeric PCR-product in the second round of PCR; hybridization upon a biochip that contains original set of oligonucleotides. The innovation enables to accelerate and simplify the technique applied.
EFFECT: higher accuracy and efficiency of identification.
16 cl, 4 dwg, 8 ex, 3 tbl
