TETRACYCLIC COMPOUNDS Russian patent published in 2020 - IPC C07D209/88 C07D307/92 C07D333/76 C07D401/06 C07D405/12 C07D471/04 C07D491/107 A61K31/403 A61K31/343 A61P35/00 

Abstract RU 2725140 C2

FIELD: organic chemistry.

SUBSTANCE: invention relates to a heterocyclic compound of formula (I) or a pharmaceutically acceptable salt thereof, where radicals A1-A5, A7-A10, R1-R10 and R6' have values given in the claim. Invention also relates to specific compounds, intermediate compounds of formula IIIb, an ALK inhibitor and a pharmaceutical composition based on the compound of formula (I).

EFFECT: obtaining a new benzocarbazole derivative effective in treating cancer.

16 cl, 49 tbl, 1218 ex

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RU 2 725 140 C2

Authors

Kinosita Kazutomo

Asokh Kokhsuke

Furuiti Noriyuki

Ito Tosiya

Kavada Khatsuo

Isii Nobuya

Sakamoto Khirosi

Khong Voosang

Park Mindzeong

Ono Esiyuki

Kato Yasukharu

Morikami Kendzi

Emura Takasi

Oikava Nobukhiro

Dates

2020-06-30Published

2010-06-09Filed