FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to novel derivatives of aminoalkanols, which can be used for manufacturing medication, applied in prevention, prophylaxis and/or treatment of diseases or symptoms of neurological origin, in particular epilepsy. Said compounds are selected from R,S-2N-[(2-chloro-6-methylphenoxy)ethyl]amino-1-butanol, R,S-2N-[(2-chloro-6-methylphenoxy)ethyl]amino-1-butanol hydrochloride, R-(-)-2N-[(2-chloro-6-methylphenoxy)ethyl]amino-1-butanol, R-(-)-2N-[(2-chloro-6-methylphenoxy)ethyl]amino-1-butanol hydrochloride, S-(+)-2N-[(2-chloro-6-methylphenoxy)ethyl]amino-1-butanol, R,S-2N-[(2,6-dimethylphenoxy)acetyl]amino-1-propanol, R-(+)-2N-[(2,6-dimethylphenoxy)acetyl]amino-1-propanol, S-(-)-2N-[(2,6-dimethylphenoxy)acetyl]amino-1-propanol, R,S-1N-[(2-chloro-6-methylphenoxy)acetyl]amino-2-butanol. Invention also relates to method of obtaining claimed compounds.
EFFECT: obtaining derivatives of aminoalkanols, which can be applied for manufacturing medication, applied in prevention, prophylaxis and/or treatment of diseases or symptoms of neurological origin, in particular epilepsy.
7 cl, 6 dwg, 6 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
NOVEL ANTIARRHYTHMIC COMPOUNDS | 1998 |
|
RU2193024C2 |
PYRIDIN-3-YL DERIVATIVES AS IMMUNOMODULATORY AGENTS | 2007 |
|
RU2454413C2 |
METHOD FOR PREPARING DERIVATIVES OF PHENYLACETIC ACID | 2000 |
|
RU2273628C2 |
PHENYL DERIVATIVES AND THEIR APPLICATION AS IMMUNOMODULATORS | 2007 |
|
RU2442780C2 |
BROMODOMAIN INHIBITORS | 2017 |
|
RU2741808C2 |
COMPOUNDS, METHOD FOR PREPARING COMPOUND, PHARMACEUTICAL COMPOSITION | 2000 |
|
RU2244709C2 |
SEMI-SYNTHETIC DERIVATIVES OF HELIOMYCIN INHIBITING TUMOR GROWTH | 2016 |
|
RU2644780C2 |
BISPHENOL DERIVATIVES AND THEIR USE AS ACTIVITY MODULATORS OF ANDROGEN RECEPTOR | 2017 |
|
RU2767257C2 |
CYCLIC AZAINDOLE-3-CARBOXAMIDE, PRODUCTION AND USE THEREOF AS THERAPEUTIC PREPARATIONS | 2009 |
|
RU2487874C2 |
AZAINDAZOLE OR DIAZAINDAZOLE DERIVATIVES AS MEDICINE | 2012 |
|
RU2600976C2 |
Authors
Dates
2014-05-10—Published
2009-01-19—Filed