METHOD FOR PREVENTING AND REDUCING DESTRUCTION OF SKELETAL PROTEINS OF ATROPHIED SKELETAL MUSCLES CAUSED BY HYPOKINESIA AND/OR DISCHARGE BY GRAVITY Russian patent published in 2014 - IPC A61K31/192 A61P21/00 

Abstract RU 2517576 C1

FIELD: medicine.

SUBSTANCE: it has been shown that in the functional muscle discharge, PD150606 blocked the calpain proteolytic system leading to the protein breakdown, which leads to prevention of atrophic processes. The invention is characterised by preventing thereby for a long period of time, as PD150606 does not decrease the NO production by the muscles. The invention can find application in space medicine to remedy the negative effect of hypokinesia or discharge by gravity.

EFFECT: reducing protein destruction of atrophied skeletal muscles caused by hypokinesia or discharge by gravity.

6 dwg

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RU 2 517 576 C1

Authors

Nemirovskaja Tat'Jana Leonidovna

Lomonosova Julija Nikolaevna

Dates

2014-05-27Published

2013-03-06Filed