RECOMBINANT EXPRESSION VECTOR ELEMENTS (REVES) TO ENHANCE EXPRESSION OF RECOMBINANT PROTEINS IN HOST CELLS Russian patent published in 2014 - IPC C07H21/04 C12N15/85 C12N15/63 C12N15/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to biotechnology and represents a recovered polynucleotide molecule with rEVE function, a recombinant expression vector, an expression shuttle vector, a host cell, as well as methods using the above recovered polynucleotide molecule. The given polynucleotide molecule with rEVE function may be used for preparing recombinant proteins. The given polynucleotide molecule with rEVE function contains a recombinant expression vector element (rEVE) containing a sequence of nucleotide bases specified in a group consisting of the nucleotide base sequence SEQ ID NO:1, the nucleotide base sequence SEQ ID NO:2, an up-regulation fragment of the sequence SEQ ID NO:1, the up-regulation fragment of the sequence SEQ ID NO:2, of the sequence complementary to any sequence as specified above, or combination thereof.

EFFECT: presented invention enables enhancing the expression of one or more proteins.

34 cl, 10 dwg, 17 tbl, 9 ex