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2 520 091

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IPC

C12N5/784(2010-01-01)

C07K14/54(2006-01-01)

A61K39/00(2006-01-01)

A61P35/00(2006-01-01)

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Application

2012135124/10, 2012-08-16

(24)

Start date

2012-08-16

(22)

Actual filing date

2012-08-16

(45)

Published

2014-06-20

(72)

Inventor

Maksjutov Amir ZakievichMaksjutov Rinat AmirovichGavrilova Elena Vasil'EvnaZajtsev Sergej AlekseevichLopatnikova Julija Anatol'EvnaSennikov Sergej Vital'EvichKurilin Vasilij Vasil'Evich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'Ju

METHOD FOR STIMULATING CYTOTOXIC IMMUNE RESPONSE TO TUMOUR CELLS OF MAMMARY ADENOCARCINOMA EXPRESSING SPECIFIC ANTIGENS, WITH USE OF DENDRITE CELLS TRANSFECTED BY POLYEPITOPE DNA CONSTRUCT Russian patent published in 2014 - IPC C12N5/784 C07K14/54 A61K39/00 A61P35/00

Abstract RU 2520091 C2

FIELD: medicine.

SUBSTANCE: invention refers to immunology, medicine and biotechnology. What is presented is a method for stimulating a specific anti-tumour immune response to breast cancer cells with the use of dendritic cells transfected by polyepitope DNA construct. The cells recovered from the peripheral blood of relatively healthy donors, transfected by the polyepitope structure are cultured with a non-adherent fraction of mononuclear cells.

EFFECT: method enables providing higher effectiveness and cost effectiveness of preparing cytotoxic lymphocytes.

1 dwg

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RU 2 520 091 C2

Authors

Maksjutov Amir Zakievich

Maksjutov Rinat Amirovich

Gavrilova Elena Vasil'Evna

Zajtsev Sergej Alekseevich

Lopatnikova Julija Anatol'Evna

Sennikov Sergej Vital'Evich

Kurilin Vasilij Vasil'Evich

Dates

2014-06-20—Published

2012-08-16—Filed