METHOD OF MICROPARTICLE FORMATION Russian patent published in 2014 - IPC A61K9/16 A61K47/42 B01J13/14 B01D9/00 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of microparticle formation. The claimed method includes providing the first anion-including solution, and providing the second cation-including solution, mixing the said first and second solutions in the presence of the first compound with a molecular weight of at least 20kDa in order to form a porous matrices. Porous matrices are formed by precipitation of salt, which contains the said anion and the said cation, with the said first compound being, at least, partially included into the porous matrices. The method includes further cross-linking of the said first compound in the porous matrices and dissolution of the porous matrices with formation of microparticles, which contain the said cross-linked first compound.

EFFECT: invention is aimed at provision of high matrix loading with the first compound, stability of the formed microparticles in water and easiness of a polymer formation, as well as preservation of function of the first compound, for instance, enzymatic activity or oxygen adsorption.

6 cl, 10 dwg, 1 tbl, 12 ex