DIAGNOSTIC TECHNIQUE FOR BENIGN AND MALIGNANT OSSEOUS GROWTHS Russian patent published in 2014 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: enzyme immunoassay is used to measure blood serum neopterin NP, vascular cellular adhesion molecules vCAM, intracellular cell adhesion molecules ICAM, tumour necrosis factor TNF-α, interleukin-6 IL-6. The coefficient K is calculated by formula: $$K=NP+\frac{\sqrt{vCAM}}{\sqrt{ICAM}}+\frac{\sqrt{TNF-\alpha }}{\sqrt{IL-6}}.$$ If K≤12.5, a benign process is diagnosed, while K>12.5 shows a malignant process.

EFFECT: using the given technique enables providing a higher objectivity of the differential diagnosis of the benign and malignant osseous growth by using a complex of the specified immunological markers.

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