METHOD FOR DIAGNOSING BREAST CANCER AND OVARIAN CANCER BY MMP-9 MRNA LEVEL IN BLOOD PLASMA Russian patent published in 2021 - IPC C12N15/00 C12Q1/68 

Abstract RU 2745424 C1

FIELD: medical biotechnology.

SUBSTANCE: invention relates to medical biotechnology. The method is based on measuring the level of MMP-9 mRNA in the blood plasma relative to the representation of the reference RNA. The obtained indicators are used to calculate the ratio of expression levels for each specific sample. The value of the obtained indicator is interpreted as a marker of early tumor formation in the mammary gland and ovaries. The invention can be used to detect early stages of breast cancer and ovarian cancer.

EFFECT: method provides a highly sensitive and objective quantitative characterization of the level of mRNA expression of MMP-9, which allows early minimally invasive diagnosis of breast and ovarian cancer.

1 cl, 2 tbl, 2 dwg

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RU 2 745 424 C1

Authors

Lolomadze Elena Anatolevna

Kometova Vlada Vladimirovna

Rodionov Valerij Vitalevich

Rebrikov Denis Vladimirovich

Dates

2021-03-25Published

2020-09-04Filed