METHOD FOR MAKING PLATE FROM MODIFIED XENOGENEIC ENTERAL SUBMUCOSA Russian patent published in 2015 - IPC A61L27/36 A61L2/25 A61L2/16 

FIELD: medicine.

SUBSTANCE: method for making a plate from modified xenogeneic enteric submucosa involves mechanical evacuation of small bowel, processing in hypertonic saline in a combination with ultrasonic exposure, enzymatic treatment, subsequent washing in acetic acid and sodium hydrocarbonate, sodium chloride processing, additional ultrasonic exposure and enzymatic treatment, storage in acetic acid and sodium hydrocarbonate, storage in an antimicrobial agent and multiply changed ascending glutaric dialdehyde. The biotissue is stored in multiply changed ascending glutaric dialdehyde in the melted form between the two plates of porous non-woven material.

EFFECT: preparing the non-immunogenic biomaterial uniformly cross linked throughout with particularly damaged collagen structure that provides the fast recipient's cell penetration into the transplant and smooth invasion of vessels and tissues in the postoperative period.

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