METHOD FOR INDIVIDUAL PREDICTION OF TEN-YEAR RISK OF FATAL CARDIOVASCULAR EVENT IN MIDDLE-AGED MALES Russian patent published in 2014 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: blood total cholesterol and triglyceride concentrations are determined. An initial heart rate, systolic (SBP) and diastolic (DBP) blood pressure are measured; a gradually increasing submaximal exercise test is conducted. The maximum and minimum DBP, SBP, the maximum heart rate at each stage of the test, as well as SBP, DBP and heart rate are measured in 30 s, 2, 4 and 6 minutes upon completion of the test. That is followed by detecting an abnormal reaction of SBP to the test with an increase of SBP less than 33 mmHg as compared to the initial SBP, or a decrease of SBP at the following stage as compared to the previous stages by more than 10 mmHg starting from the third stage. The abnormal delayed post-exercise heart rate recovery with a decrease of the heart rate by less than 8 beats/min for the first minute or by less than 12 beats/min for the first two minutes after completion of the exercise is determined. The test length is recorded. A ten-year risk of the fatal cardiovascular event is calculated by formula taking into account the above parameters.

EFFECT: invention enables reliable individual prediction taking into account all the hemodynamic parameters specified above and ensures avoiding false positive and false negative results.

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