CARDIOVASCULAR HOMOGRAFT (VERSIONS), METHOD FOR PREPARING HOMOGRAFT, HOMOGRAFT TISSUE EXPOSURE MEDIUM (VERSIONS) Russian patent published in 2014 - IPC A61F2/06 A01N1/02 A61K31/7036 A61P43/00 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to cardiac surgery, and concerns creating cardiovascular homografts (CVHG) applied as vascular biological prostheses in cardiovascular surgeries. There are presented versions of a homograft representing a great vessel section or right and left ventricular outflow tracks taken from a dead body. The homograft is also characterised by min. 30-minute preparation in a medium containing gentamycin, diflucan and pH stabiliser. At a stage of preparation the homograft is processed with a medium of pH 7.0-7.4 representing a DMEM/F12 solution and containing gentamycin, diflucan, cephalosporin and metrogyl. Further, the homograft is kept in a medium containing the DMEM/F12 solution, gentamycin, diflucan and a phosphate buffer. There are also presented methods for producing the CVHG versions, as well as the media for the homograft treatment at the various stages of producing, keeping and handling.

EFFECT: creating the CVHG of more rigid structures resistant to damaging factors of the treatment, handling and storage media that improves their body functions.

16 cl, 10 ex, 9 tbl, 10 dwg