FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely therapy and endocrinology, and can be used for glycaemia monitoring. Glycaemia values are indirectly shown by measured temperature and/or thermal flows by means of sensors of a measuring instrument in the region of superficial veins of the head. That is followed by a pre-calibration of the given blood glucose levels derived by the non-invasive method and the measured values by formula: Xg *=X1 *+X2 *, wherein X1 *=KtfWtf(s)Xt *, X2 *=KfWtf(s)Xf *, wherein Xt * is a non-dimensional temperature overshoot, Xf * is a non-dimensional thermal flow overshoot, Wtf(s)=e-τs is a transfer function of the blood glucose level shown by temperature and the thermal flow, τ is a blood glucose change delay in relation to temperature overshoot, Ktf, Kf are calibration coefficients, s=d/dt is a differentiation operator. The calibration coefficients and the delay time are adjusted automatically by data randomly supplied to a calculation unit and derived by the non-invasive method.
EFFECT: method enables high-accuracy glycaemia monitoring by systematic adjustment of the calibration coefficients and the delay time.
3 cl, 2 tbl, 2 ex, 2 dwg
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Authors
Dates
2014-08-20—Published
2011-12-12—Filed