DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR ALCOHOLIC LIVER DISEASE Russian patent published in 2014 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: invention may be used in therapy for differential diagnosis of the alcoholic liver disease (ALD). The technique involves serum analysis to measure serum secretory immunoglobulin A (ssIgA) and total immunoglobulin E (IgE) by enzyme-linked immunosorbent assay, and if the ssIgA concentration is more than 5.47 mg/l and the IgE concentration is more than 25 IU/ml, the alcoholic liver disease is diagnosed; if the ssIgA concentration is 5.47 mg/l or less, and the IgE concentration is 25 IU/ml or less, the non-alcoholic fatty liver disease (NAFLD) is diagnosed.

EFFECT: technique has high-sensitivity and specificity, requires no additional blood sampling procedures necessary for determining the most biochemical values measured in the patients with the suspected ALD, and it also enables differentiating the ALD and the NAFLD.

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