FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to a method of measuring troponin I in a sample. For this purpose the sample is provided. After that, the sample is brought in contact with a monoclonal antibody to troponin I, bound with a magnetic label. Then, the sample is brought in contact with the polyclonal antibody or with two different antibodies to troponin I, bound with a sensor surface. The said antibodies are aimed at an amino acid sequence 30-110 of troponin I. After that, the detection of the magnetic label on the sensor surface is carried out. The group of inventions also relates to a device and a cartridge for measuring troponin I in the sample.
EFFECT: inventions make it possible to carry out diagnostics of myocardium infarction within 5 minutes and with the application of the small-volume sample.
14 cl, 2 dwg
Title | Year | Author | Number |
---|---|---|---|
DEVICE AND METHODS OF DETECTING ANALYTES IN SALIVA | 2009 |
|
RU2530718C2 |
FAST BIOSENSOR WITH REAGENT LAYER | 2007 |
|
RU2482495C2 |
MULTI-LAYERED ANALYSIS WITH HORIZONTAL FLOW WITH PRESS FOR SAMPLES | 2010 |
|
RU2564911C2 |
METHOD FOR DETECTION OF PROTEINS | 2012 |
|
RU2606852C2 |
ANALYSIS FOR GLYCATED PROTEINS | 2015 |
|
RU2698311C2 |
ANTIBODIES AGAINST HUMAN IgG1 | 2011 |
|
RU2603284C2 |
USING GLYCOSAMINOGLYCANS FOR DECREASING NON-SPECIFIC BINDING IN IMMUNOLOGICAL ASSAYS | 2008 |
|
RU2490648C2 |
REAGENT FOR RELEASE OF VITAMIN D | 2011 |
|
RU2579312C2 |
METHODS FOR DETECTING APOLIPOPROTEINS | 2016 |
|
RU2763404C2 |
TARGET MOLECULE DETECTION IN SAMPLE | 2007 |
|
RU2444736C2 |
Authors
Dates
2014-10-10—Published
2009-12-15—Filed