METHODS AND COMPOSITIONS DESCRIBED AS SYNTHETIC BETA-1,6-GLUCOSAMINOLIGOSACCHARIDES Russian patent published in 2014 - IPC C07D207/456 C07C327/20 C07C327/32 C07H3/06 C08B37/00 C07K14/31 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to oligosaccharide carrier conjugates effective for treating and preventing infectious diseases and containing an oligosaccharide conjugated with the carrier through a linker of formulas

VIIIa

or

VIIIb:

wherein n is more than 1, m is specified in 1-10, p is specified in 1-20 and R represents H or alkyl; the linker is bound to an oligosaccharide oxygen atom through a terminal CH₂ group, and the linker is bound through a terminal CO group with an amino group of the carrier compound by an amide bond; the oligosaccharide is β-1-6 related glucosamine, and the carrier is peptide, protein, polysaccharide, nucleic acid, lipid or tetanus toxoid.

EFFECT: there are presented new conjugates effective to stimulate the immune response, and a method for preparing them.

21 cl, 12 ex, 23 dwg, 1 tbl