METHOD FOR DETERMINING SEVERITY OF DISEASE IN CHILDREN SUFFERING FROM INFANTILE CEREBRAL PARALYSIS Russian patent published in 2014 - IPC G01N33/577 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to child neurology. A method includes detecting the clinical signs of a disease, measuring erythrocytes with micronuclei in a child's peripheral blood. The novel in the method for determining a degree of severity of the disease in the children with ICP is that the clinical signs of the disease are assessed by the Rivermead Mobility scale, and then an enzyme immunoassay is used to determine the qualitative content of the tumour necrosis factor (TNF-α) in the ICP children's saliva; the measured and determined values are compared to the clinical signs, and if the measured erythrocytes with micronuclei make 0.55±0.14%, saliva TNF-α increases to 13.23±5.2 pg/ml, a moderate severity is stated, while erythrocytes with micronuclei making 1.27±0.87% and more, and saliva TNF-α being 25.41±5.42 pg/ml and more show the severe disease.

EFFECT: invention enables providing the simple, non-invasive, accessible instant method for determining a degree of severity of the disease and prescribing the timely treatment.

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