METHOD OF PREVENTING CEREBRAL FORM OF RADIATION SICKNESS Russian patent published in 2014 - IPC A61K31/4965 A61P39/06

Abstract RU 2537170 C1

FIELD: medicine.

SUBSTANCE: invention relates to medical radiology and can be used for prevention of cerebral form of acute radiation sickness. Claimed is application of officinal drug pyrazinamide as medication for prevention of cerebral form of acute radiation sickness. Pyrazinamide has been used for treating tuberculosis.

EFFECT: preventing in 100% of cases development of early temporary incapacity in case of irradiation in dose 200 Gy, improvement of indices of behavioral and research activities in irradiated animals, in reduction of frequency of motor disorders, reduction of frequency and expression of convulsive-hyperkinetic syndrome and 9,5 fold increase of average life expectancy of irradiated animals Pyrazinamide is not inferior to drug - nicotinamide prototype in efficiency of radioprotective action.

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RU 2 537 170 C1

Authors

Drachev Igor' Sergeevich

Krasil'Nikov Igor' Ivanovich

Kraev Sergej Jur'Evich

Dates

2014-12-27—Published

2013-11-20—Filed