METHOD OF PRE-OPERATION DIAGNOSTICS OF PARATHYROID GLAND ADENOMA Russian patent published in 2014 - IPC A61B6/03 A61K49/04 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, diagnostics of adenoma of parathyroid glands (PTG), and can be applied in radiodiagnostics, endocrinology, surgery. Multi-phase multispiral computed tomography (MSCT) with X-ray contrast preparation (RC) is carried out at arterial and venous phases of analysis - respectively at 25 and 50 seconds after RC introduction. reading of parameters, analysis of obtained images and pre-operation diagnostics of patient's state are performed. RC is introduced single time, after its introduction physiological solution is introduced intravenously, with introduction of preparations through catheter at rate 4±1 ml/s. Visual and densitometric analysis of obtained images are performed in analysis of obtained images. As analysis parameters determined are: coefficient of radiation attenuation in all formation of the area under examination, suspicious of PTG adenoma. Presence of adenoma is diagnosed with fixation of X-ray radiation attenuation coefficient to +180+200 HU at early arterial phase and detection of not less than 80 HU density reduction at venous stage.

EFFECT: method provides improvement, high quality of diagnostics of PTG adenomas due to more accurate fixation of neoplasm location, optimal distribution and retention of contrast substance in the zone of examination in healthy and pathogenic zones, which makes it possible to reduce operation time to 15 minutes instead of 60 minutes, reduce post-operation period from 5 days to 1 day.

6 dwg, 4 ex