METHOD FOR DETERMINING LEVEL OF TOXICANTS IN WATER, FOOD PRODUCTS OR PHYSIOLOGICAL LIQUIDS, AND TEST SYSTEM Russian patent published in 2015 - IPC G01N33/18 

Abstract RU 2538707 C1

FIELD: biotechnologies.

SUBSTANCE: carrier is arranged in a column of a test system in the form of a layer of immunoaffinity gel, which is fixed between two porous membranes and provided with grafted - covalently bound - molecules of a toxic agent; the carrier - the gel layer is treated with a blocking solution for closure on the carrier of the rest free places of nonspecific binding; test specimens containing a certain amount of pre-introduced antibodies specific to a toxicant are added; the carrier is treated with a conjugate-containing solution, and namely a conjugate solution of anti-species antibodies chemically bound to luminescent quantum dots or to liposomes containing luminescent quantum dots, and a level of toxicants is determined by illumination of the treated carrier with excitation radiation as to intensity of luminescence excited at quantum dots.

EFFECT: group of inventions allows effective and reliable determination of a level of toxicants in water, food products or physiological liquids.

4 cl, 1 dwg, 3 ex

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RU 2 538 707 C1

Authors

Grebennikov Evgenij Petrovich

Beloglazova Natalija Vladimirovna

Gorjacheva Irina Jur'Evna

Kurbangaleev Vagiz Ravilevich

Speranskaja Elena Sergeevna

Shmelin Pavel Sergeevich

Dates

2015-01-10Published

2013-08-21Filed