METHOD OF PRODUCING COMPOSITE BIODEGRADABLE MATERIALS BASED ON CHITOSAN AND POLYLACTIDE Russian patent published in 2015 - IPC A61L15/62 A61L15/28 C08F251/00 

FIELD: chemistry.

SUBSTANCE: invention relates to biotechnology and medicine, and specifically to a method of producing film-type and composite materials based on chitosan and polylactide, which are biodegradable, biocompatible and hypoallergenic. Described is a method of producing composite biodegradable materials based on chitosan and polylactide, which includes preparing polysaccharide and polylactide solutions using a mixed solvent, wherein the chitosan solution is mixed with 10-50% polylactide solution with respect to the mass of chitosan while stirring continuously. The obtained mixture is subjected to ultrasonic treatment until a block-copolymer of chitosan and polylactide is obtained. Disclosed materials can be used in articles for biomedical purposes, including osteosynthesis materials and prolonged action medicinal drug carriers.

EFFECT: obtained materials are used for osteosynthesis based on natural and synthetic polymers, decomposition products of which prevent the development of toxic, inflammatory and allergic reactions in tissue owing to use of a chitosan biopolymer.

2 cl, 1 tbl, 5 ex