FIELD: medicine.
SUBSTANCE: environmentally unfriendly territory is selected; a sensitive group of 14-17-year-old adolescents are detected to measure relative IgG antibodies to main organ and tissue antibodies: LuM-02, KiM-05, GaM-02, ItM-07, HMMP, CoM-02, β-adrenoreceptors, TrM-03, ANCA, thyroglobulin, insulin, and to antigens characterising the nerve: S100, GFAP, and immune systems: native DNA, beta2-glycoprotein I and IgG Fc-fragment. An average immune reactivity of these antibodies is calculated; a deviation of the relative beta2-glycoprotein I antibody levels from the average immune reactivity is derived. The blood serum alpha-1 antitrypsin level, an erythrocyte sedimentation rate (ESR) are determined, and a diagnostic coefficient is calculated by formula: Y=0.521+0.012×A+0.013×B-0.017×C+0.003×D; wherein Y is the diagnostic coefficient, A is the average immune reactivity, %, B is the deviation of the relative beta2-glycoprotein I antibody level from the average immune reactivity, %, D is the blood serum alpha-1 antitrypsin level, mg/dl, C is the erythrocyte sedimentation rate, mm/h. If Y is more than (-0.6) and less than 0.23, the presence of a chronic upper airway disease with no man-induced impact is stated. If Y is more than 0.24 and less than 0.71, the presence of a chronic upper airway disease with an identified man-induced impact is stated. If Y is more than 0.72 and less than 1.4, a chronic upper airway disease is considered to be associated with a man-induced impact.
EFFECT: using the given method enables detecting the chronic upper airway pathology by measuring the laboratory values.
2 tbl, 2 dwg, 4 ex
