METHOD OF PRODUCING CROSSLINKED GEL Russian patent published in 2015 - IPC C08J3/24 A61K8/73 A61K31/738 A61Q19/08 A61J1/10 

FIELD: chemistry.

SUBSTANCE: invention relates to a novel method of producing hydrogels based on a crosslinked polymer, particularly obtained from polysaccharide or from one salt thereof. The method of producing crosslinked gel includes at least a step of: a) obtaining an aqueous medium containing at least one polysaccharide, b) forming a homogeneous gel from the medium obtained at step (a), c) bringing the gel obtained at step (b) into contact with an effective amount of at least one crosslinking agent, d) crosslinking said mixture formed at step (c), and e) extracting said crosslinked hydrogel. At least said steps (a) to (d) are carried out in a sealed chamber, bounded at least in part by a deformable wall, wherein said mixture in the chamber undergoes step (d) at conditions which facilitate crosslinking.

EFFECT: method improves homogenisation of the polymer before crosslinking and improves the correct progression of the crosslinking process.

19 cl, 7 dwg, 3 tbl, 3 ex