FIELD: medicine.
SUBSTANCE: strain is deposited from pulmonary tissue homogenate of guinea pigs infected by the 7th passage of smallpox virus. The strain is deposited in the State Collection of Agents of Viral Infections and Rickettsial Diseases of State-Financed Research Institution State Scientific Centre of Virology and Biotechnology Vector of Federal Service for Supervision for Consumer Rights Protection and Human Welfare, registration No. V-624. The strain causes an acute lethal infection with the more manifested clinical pattern in guinea pigs 200-300g heavy infected intranasally, thereby modelling smallpox in a human.
EFFECT: strain can be used for studying in vivo the efficacy of the antiviral preparations and assessing the reduction routines of undesired vaccine reactions and complications accompanying primary smallpox vaccination.
3 tbl, 2 ex
| Title | Year | Author | Number |
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| AGENT FOR ARRESTING UNDESIRABLE VACCINAL REACTIONS AND COMPLICATIONS DURING PRIMARY VACCINATION WITH VARIOLAR VACCINES AND METHOD FOR USE THEREOF | 2013 |
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