METHOD FOR DETERMINING FUNCTIONAL ACTIVITY OF HUMAN COMPLEMENT COMPONENT C4 Russian patent published in 2015 - IPC G01N33/53 

Abstract RU 2542404 C1

FIELD: medicine.

SUBSTANCE: cell suspension of Tetrahymena pyriformis, a test sample and R4 agent representing a human blood serum with selectively deactivated component C4 by hydrazine hydrate processing are introduced into measuring cells of automated living infusorians counting device to determine a living cell count a minute. A progressing decrease of the living cell count through time is used to calculate a first-order reaction rate constant with determining a slope of living cell count log and time dependence in the period of the observed decrease of the living cell count. The calculated decrease rate constant through time is linearly dependent on component C4 activity.

EFFECT: invention is effective for diagnosing a number of component C4 activity related diseases.

2 cl, 1 dwg, 1 ex

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RU 2 542 404 C1

Authors

Kozlov Leonid Vasil'Evich

Kuleshina Ol'Ga Nikolaevna

Dates

2015-02-20Published

2013-11-06Filed