FIELD: medicine.
SUBSTANCE: method comprises bringing of the said cross-linked collagen biomaterial into contact with a sterilisation solution containing 3%-6% v/v of propylene oxide, and maintaining of the said biomaterial in a thermostat in propylene oxide at a temperature of 30°C to 55°C for more than 48 hours. The solution for sterilisation does not contain alcohol. A method for collagen-based biomaterial sterilisation, a method for collagen-based cross-linked biomaterial storage, and versions of sterilized collagen-based cross-linked biomaterial are disclosed as well.
EFFECT: increased efficiency of sterilisation, provision of a suitable environment for sterilized material storage.
13 cl, 2 dwg, 7 tbl, 9 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF PREVENTING DECOMPOSITION AND DEGENERATION OF TISSUE USED IN BIOPROSTHESIS | 2019 |
|
RU2809478C2 |
METHOD OF PROCESSING GRAFTS FOR CARDIOVASCULAR SURGERY USING SUB- AND SUPERCRITICAL CARBON DIOXIDE | 2022 |
|
RU2796364C1 |
METHOD OF PRODUCING ENZYMATICALLY RESISTANT COLLAGEN MATERIALS | 2019 |
|
RU2739565C1 |
METHOD OF PRODUCTION OF PENTAGLYCIDYL ETHER OF GLUCOSE AND COMPOSITION BASED ON IT FOR CHEMICAL LINKING OF COLLAGEN-CONTAINING ENDOPROSTHESES OF BIOLOGICAL ORIGIN | 2014 |
|
RU2563251C1 |
COLLAGEN SPONGE | 2015 |
|
RU2672593C1 |
METHOD FOR MANUFACTURE OF VALVE-CONTAINING CONDUIT FROM CATTLE JUGULAR VEIN | 2016 |
|
RU2633544C1 |
METHOD FOR MAKING BIOLOGICAL VENOUS-VALVE PROSTHESIS | 2010 |
|
RU2429023C1 |
POLYMER WOVEN SEALANT | 2008 |
|
RU2453340C2 |
METHOD FOR PRE-IMPLANTATION TREATMENT OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2023 |
|
RU2827028C1 |
HAEMOSTATIC SPONGE | 2011 |
|
RU2562569C2 |
Authors
Dates
2017-09-15—Published
2012-11-09—Filed