FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine. What is described is a transdermally absorbable formulation prepared by dissolving donepezil in an adherent plaster base, which contains a hydrophobic polymer and an absorption enhancer. The absorption enhancer represents one substance, or two or more substances specified in lauryl alcohol, triethyl citrate, isopropylmyristate, cetyl lactate, oleyl alcohol, sorbitan monooleate, polyethyleneglycol monostearate, lauromacrogol, N-methyl-2-pyrroldone and triacetin.
EFFECT: transdermally absorbable formulation can administer donepezil stably for a relatively long period of time and can provide both blood donepezil increase, and the properties of sustained release of donepezil.
4 cl, 4 dwg, 6 tbl, 26 ex
| Title | Year | Author | Number |
|---|---|---|---|
| RUPATADINE-CONTAINING PATCH | 2018 |
|
RU2776063C2 |
| EXTERNAL FLUORBIPROPHENE-CONTAINING PLASTER | 2005 |
|
RU2382641C2 |
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|
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| EXTERNAL PREPARATION | 2020 |
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| TRANSCUTANEOUS SUCTION COMPOSITION | 2016 |
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| ESTRADIOL-CONTAINING TRANSDERMAL THERAPEUTIC SYSTEM | 1994 |
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| TAPE-APPLIED PHENTHANYL-CONTAINING PREPARATION FOR PERCUTANEOUS USAGE | 1997 |
|
RU2194496C2 |
| TRANSDERMAL THERAPEUTIC SYSTEM | 1989 |
|
RU2011384C1 |
