METHOD FOR ELECTROCHEMICAL IMMUNOASSAY FOR DETECTING VIRUSES/VIRAL ANTIGENS Russian patent published in 2015 - IPC G01N33/58 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention involves the sandwich-type immune complex formation between antibodies and measles virus/viral antigen followed by attaching an antibody conjugate with a signal-forming label; the signal-forming label represents magnetic nanocomposite particles that are produced by the silicon oxide coating formation on the surface of the magnetic nanoparticles of transition metal oxide, which is supposed to be conjugated with the antibodies; before the stage of the immune complex formation. The immune complex is formed by concentrating it on a solid-phase chemically inert carrier as a result of the magnetic field exposure, which is followed by removing this immune complex from a medium formed on a medium formed on the carrier; the virus/viral antigens and their concentration are detected and measured by a signal generated by transient metal ions formed by the acid treatment of the immune complex.

EFFECT: simplifying the analytical procedure, increasing the rate and reproducibility.

3 cl, 4 dwg, 3 ex