FIELD: medicine.
SUBSTANCE: invention refers to medicine and aims at diagnosing vaginitis in females of a reproductive age. Expression levels of mRNA of TNF, IL18, GATA3 and TLR4 genes are measured in vaginal smears. Expression levels of mRNA of TLR4/GATA3 and TNF/IL18 genes are related, and the derived threshold cycles are used to predict a probability of vaginitis by formula. If P≤57% for nonpregnant females or P≤68.5% for pregnant females, the absence of vaginitis is stated. If P≥57% for nonpregnant females or P≥68.5% for pregnant females, vaginitis is diagnosed.
EFFECT: invention provides the effective diagnosis of vaginitis in the females of a reproductive age.
3 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DIAGNOSTIC TECHNIQUE FOR VAGINITIS IN PREGNANT WOMEN BY INTERLEUKINE GENE IRNA EXPRESSION IN VAGINAL SMEARS | 2011 |
|
RU2510855C2 |
| PREDICTION OF PREMATURE BIRTH BASED ON GENE EXPRESSION PROFILE OF INNATE IMMUNITY IN CERVICAL CELLS | 2016 |
|
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| METHOD OF DIAGNOSTICS OF POSTPARTUM ENDOMETRITIS USING THE RT-PCR | 2017 |
|
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| METHOD FOR PREDICTION OF PRETERM DELIVERY IN MULTIPLE PREGNANCIES | 2020 |
|
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| METHOD FOR DIAGNOSING BREAST CANCER BY LEVEL OF EXPRESSION OF IL-10 AND/OR IL-17 MRNA IN BLOOD PLASMA | 2020 |
|
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| METHOD FOR PREDICTING OF MISCARRIAGE OF INFECTIOUS GENESIS AT EARLY STAGES OF GESTATION | 2016 |
|
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| METHOD FOR EARLY NEONATAL SEPSIS DIAGNOSIS FOR NEWBORNS ON FIRST DAY OF LIFE BASED ON MRNA EXPRESSION PROFILE IN BUCCAL SCRAPE CELLS | 2016 |
|
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| METHOD FOR DIAGNOSING BREAST CANCER BY LEVEL OF MRNA TGEβ AND TNFα IN BLOOD PLASMA | 2019 |
|
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| METHOD FOR DIAGNOSING BREAST CANCER AND OVARIAN CANCER BY MMP-9 MRNA LEVEL IN BLOOD PLASMA | 2020 |
|
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| DIAGNOSTIC TECHNIQUE FOR INFLAMMATORY PROCESS IN EARLY RHEUMATOID ARTHRITIS | 2009 |
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RU2417263C2 |
