METHOD FOR PRODUCING CARBONATE HYDROXYL APATITE GRANULES IN GELATINE MATRIX Russian patent published in 2015 - IPC A61K9/16 A61L27/46 

Abstract RU 2552756 C1

FIELD: medicine.

SUBSTANCE: what is presented is a method for producing carbonate hydroxyl apatite granules consisting in mixing carbonate hydroxyl apatite powder with aqueous solution of gelatine 5 wt % in ratio of the power 1 g to the solution 7.5 ml until smooth; the produced mixture is dispersed through a capillary of a diameter of 1÷2 mm into vegetable oil cooled down to a temperature of T1=-1÷0°C; the produced granules are decanted from the oil and washed with a mixture of ethanol and acetone in ratio 2:1, dried at a temperature of T2=25÷27°C in the air for t=5÷7 hours to hold a spherical shape. The carbonate hydroxyl apatite granules held their spherical shape within the range of 400-800°C, have a diameter of 1-2 mm, specific surface within the range of 32-0.04 m2/g and mesopore volume within the range of 0-0.098 cm3/g.

EFFECT: maintaining the qualities.

1 tbl, 3 ex

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RU 2 552 756 C1

Authors

Izmajlov Rinat Rashidovich

Golovanova Ol'Ga Aleksandrovna

Dates

2015-06-10Published

2014-04-28Filed