METHOD FOR ANTI-IMMUNOGLOBULIN E ANTIBODY NEUTRALISATION ACTIVITY TEST Russian patent published in 2015 - IPC G01N33/53 

Abstract RU 2554820 C2

FIELD: medicine.

SUBSTANCE: invention refers to immunology and represents a method for anti-immunoglobulin E antibody neutralisation activity test, which consists in binding the test antibodies with human IgE in a solution, incubating the above solution with human peripheral blood, inducing cell degranulation and determining a cell portion having a high expression level of CD63 (CD63high) surface marker in a basophile population with phenotype CD123+HLA-DR-.

EFFECT: invention enables considerably reducing the length of analysis and its labour intensity.

2 dwg, 2 ex

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RU 2 554 820 C2

Authors

Petrov Aleksandr Vladimirovich

Sineva Svetlana Adamovna

Trofimov Aleksandr Viktorovich

Sharafutdinova Tat'Jana Ajratovna

Simbirtsev Andrej Semenovich

Dates

2015-06-27Published

2013-10-15Filed