FIELD: medicine.
SUBSTANCE: invention refers to immunology and represents a method for anti-immunoglobulin E antibody neutralisation activity test, which consists in binding the test antibodies with human IgE in a solution, incubating the above solution with human peripheral blood, inducing cell degranulation and determining a cell portion having a high expression level of CD63 (CD63high) surface marker in a basophile population with phenotype CD123+HLA-DR-.
EFFECT: invention enables considerably reducing the length of analysis and its labour intensity.
2 dwg, 2 ex
Title |
Year |
Author |
Number |
METHOD AND SET FOR DETERMINATION OF ALLERGEN-INDUCED ACTIVATION OF BASOPHILS IN ASSAY OF HYPERSENSITIVITY TO SOME SUBSTANCES |
2002 |
|
RU2273029C2 |
FcγRIIB RECEPTOR ANTIBODIES AND APPLICATION THEREOF |
2005 |
- Chan Ehndrju K.
- Shilds Robert L.
- Vu Loren
|
RU2404991C2 |
METHOD FOR DETERMINING SUBPOPULATION COMPOSITION OF SKIN CELLS AND OBTAINING SKIN CYTOIMMUNOGRAM |
2016 |
- Goltsov Sergej Viktorovich
- Kostolomova Elena Gennadevna
- Sukhovej Yurij Gennadevich
- Pauls Vyacheslav Yurevich
|
RU2630607C1 |
ISOLATED ANTIBODY OR ITS ANTIGEN-BINDING FRAGMENT SPECIFIC FOR HUMAN IMMUNOGLOBULIN E (VERSIONS), NUCLEIC ACID MOLECULE CODING IT, HOST CELL, METHOD FOR PREPARING ANTIBODY OR ITS ANTIGEN-BINDONG FRAGMENT, PHARMACEUTICAL COMPOSITION, USE THEREOF FOR TREATING IgE-ASSOCIATED DISEASES |
2008 |
- Kochrejn Dankan
- Koehn Suzann
- Dobson Klehr Luisa
- Ehriksson Per-Ulaf Fredrik
- Monk Fillip Dejvid
- Fon-Vakhenfel'Dt Karin
|
RU2466140C2 |
METHODS OF TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES BY MEANS OF 2,4-PYRIMIDINDIAMIN COMPOUNDS |
2003 |
- Singkh Radzhinder
- Argade Ankush
- Pehjan Donal'D Dzh.
- Klaf Dzheffri
- Kajm Kholger
- Silvehn Katrin
- Li Khuehj
- Bkhamidipati Somasekkhar
|
RU2376992C2 |
IMPROVED ANTI-IGE-ANTIBODY (VARIANTS) AND METHOD FOR IMPROVING POLYPEPTIDES |
1998 |
- Louman Khenri B.
- Presta Leonard G.
- Zhard'E Paula M.
- Lou Dzhon
|
RU2242515C2 |
FUSED POLYPEPTIDE OR ITS SALT, EXPRESSING VECTOR AND PHARMACEUTICAL COMPOSITION DESIGNATED FOR TREATMENT OF IGE-MEDIATED DISEASES |
1997 |
- Digan Mehri Ehllen
- Lejk Filip
- Gram Germann
|
RU2209211C2 |
METHODS AND COMPOSITIONS FOR IMPROVING EFFECTIVENESS OF ANTIBODY FOR MEDICAL APPLICATION WITH USING COMPOUNDS POTENTIATING NK-CELLS |
2004 |
- Velardi Andrea
- Roman' Fransua
|
RU2396981C2 |
METHOD FOR DETECTION OF IgE-PRODUCING B-LYMPHOCYTES |
1988 |
- Tse-Ven Chang[Tw]
- Bill San[Us]
- Sesili San[Us]
|
RU2047177C1 |
COMPOSITION CONTAINING PROBIOTICS AND POLYPEPTIDE HAVING BINDING AFFINITY RELATIVELY TO IgE AND ITS USE |
2019 |
- Jang, Myoung Ho
- Sung, Young Chul
- Yang, Zungyoon
|
RU2786578C2 |