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(19)

(11)

2 554 820

(13)

(51)

IPC

G01N33/53(2006-01-01)

(21) (22)

Application

2013145847/15, 2013-10-15

(24)

Start date

2013-10-15

(22)

Actual filing date

2013-10-15

(45)

Published

2015-06-27

(72)

Inventor

Petrov Aleksandr VladimirovichSineva Svetlana AdamovnaTrofimov Aleksandr ViktorovichSharafutdinova Tat'Jana AjratovnaSimbirtsev Andrej Semenovich

(73)

Holder

Federal'Noe Gosudarstvennoe Unitarnoe Predprijatie Nauchno-Issledovatel'Skij Institut Osobo Chistykh Biopreparatov" Federal'Nogo Mediko-Biologicheskogo Agentstva

METHOD FOR ANTI-IMMUNOGLOBULIN E ANTIBODY NEUTRALISATION ACTIVITY TEST Russian patent published in 2015 - IPC G01N33/53

Abstract RU 2554820 C2

FIELD: medicine.

SUBSTANCE: invention refers to immunology and represents a method for anti-immunoglobulin E antibody neutralisation activity test, which consists in binding the test antibodies with human IgE in a solution, incubating the above solution with human peripheral blood, inducing cell degranulation and determining a cell portion having a high expression level of CD63 (CD63^high) surface marker in a basophile population with phenotype CD123⁺HLA-DR^-.

EFFECT: invention enables considerably reducing the length of analysis and its labour intensity.

2 dwg, 2 ex

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RU 2 554 820 C2

Authors

Petrov Aleksandr Vladimirovich

Sineva Svetlana Adamovna

Trofimov Aleksandr Viktorovich

Sharafutdinova Tat'Jana Ajratovna

Simbirtsev Andrej Semenovich

Dates

2015-06-27—Published

2013-10-15—Filed