METHOD OF PRODUCING 4-HYDROXY-5-(R-1H-PYRAZOLE)-BENZENE-1,2-DICARBONITRILES Russian patent published in 2015 - IPC C07D231/12 C07D231/20 C07D401/04 C07D409/04 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 4-hydroxy-5-(R-1H-pyrazole)-benzene-1,2-dicarbonitriles of general formula , given below, where R=OH, or CH₃, or C₆H₅, or 4-CH₃C₆H₄, or 4-OCH₃C₆H₄, or 2-thienyl; R₁=CH₃, or C₆H₅, or 3-pyridyl; R₂=H or C₆H₅. Said compounds can be used as precursors for synthesis of biologically active substances and for synthesis of phthalocyanines and hexazocyclanes. The method of producing 4-hydroxy-5-(R-1H-pyrazole)-benzene-1,2-dicarbonitriles includes reacting substituted benzofuran-5,6-dicarbonitriles with a hydrazine hydrate or phenylhydrazine.

EFFECT: use of the disclosed synthesis method enables to obtain novel ortho-dicarbonitriles containing a pyrazole ring.

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