FIELD: chemistry.
SUBSTANCE: invention relates to method of obtaining substituted 3-formylindole-5,6-dicarbonitriles where R = ALK, or Ar, or Het, which can be applied as precursors for synthesis of biologically active substances, medicinal substances. Method of obtaining 3-formylindole-5,6-dicarbonitriles consists in interaction of 2-substituted 1-methoxyindole-5,6-dicarbonitriles with phosphoryl-chloride.
EFFECT: application of claimed method of synthesis of substituted 3-formylindole-5,6-dicarbonitriles makes it possible to obtain novel ortho-dicarbonitriles, which contain indole cycle, which have not been described in literature before.
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Authors
Dates
2015-12-10—Published
2014-12-09—Filed