FIELD: medicine.
SUBSTANCE: implant layers are presented in the form of congruent ellipsoids of rotation consisting of polymers and/or copolymers of glycosaminoglycans, lactic acid and polyvinylpyrrolidone; all drug-saturated layers are alternated with drug-unsaturated layers, while solubility of each implant layer is provided by hydrolysis of cross linkage and directly proportional to their number.
EFFECT: achieving and maintaining the required drug concentration in the vitreal cavity for the required period of time, no risk of damaging the intraocular structures with high-concentrated drug substances, reducing the intraoperative injury.
2 cl
| Title | Year | Author | Number | 
|---|---|---|---|
| MULTILAYER BIODEGRADABLE OCULAR IMPLANT WITH DOSED DRUG RELEASE AND METHOD OF ITS MANUFACTURE | 2015 | 
 | RU2620249C1 | 
| METHOD FOR DRUG DELIVERY TO POSTERIOR EYEBALL SEGMENT STRUCTURES | 2015 | 
 | RU2583599C1 | 
| METHOD OF TREATING ATROPHIC AGE-RELATED MACULAR DEGENERATION | 2009 | 
 | RU2521338C9 | 
| METHOD FOR TREATING ATROPHIC AGE RELATED MACULAR DEGENERATION | 2009 | 
 | RU2668371C2 | 
| INTRAOCULAR IMPLANTS CONTAINING PROSTAMIDES | 2014 | 
 | RU2666603C2 | 
| INTRAOCULAR DRUG DELIVERY SYSTEMS | 2007 | 
 | RU2440102C2 | 
| METHOD FOR STIMULATING NEOVASCULARISATION OF RETINA AND OPTIC NERVE IN RABBITS | 2009 | 
 | RU2408083C1 | 
| BIODEGRADABLE DRUG DELIVERY SYSTEMS FOR LONG-TERM RELEASE OF PROTEIN | 2013 | 
 | RU2676102C2 | 
| DEXAMETHASONE CONJUGATE WITH SYNTHETIC STATISTICAL POLYPEPTIDE | 2020 | 
 | RU2792146C2 | 
| EYE IMPLANTAT PREPARED BY DOUBLE EXTRUSION METHOD | 2005 | 
 | RU2389479C2 | 
Authors
Dates
2015-07-27—Published
2014-03-17—Filed