FIELD: chemistry.
SUBSTANCE: invention relates to method of obtaining derivatives of carboxylic acids, in particular to novel method of reamidating amides of carboxylic acids. Method is realised by interaction of carboxylic acid amide with amine with heating in presence of catalyst - copper nanoparticles. As carboxylic acid amide formamide, acetamide, dimethylformamide or isovaleramide is applied, as amine - cyclohexylamine, piperidine, morpholine or 2-aminoethanol. Process is carried out with molar ratio carboxylic acid amide : amine : catalyst, equal 1:1-1.2:0.02-0.05, at temperature 20-100°C for 0.5-3 hours.
EFFECT: simplified method of reamidation of carboxylic acid amides due to application of cheaper catalyst and carrying out process in milder conditions.
8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING CARBOXYLIC ACID AMIDES | 2014 |
|
RU2565059C1 |
| METHOD OF PRODUCING CYCLOALKYLAMINES | 2010 |
|
RU2425828C1 |
| METHOD OF PRODUCING BENZANILIDE | 2019 |
|
RU2712053C1 |
| METHOD OF PRODUCING AROMATIC AMIDES OF 1-ADAMANTANE CARBOXYLIC ACID | 2019 |
|
RU2698193C1 |
| METHOD OF PRODUCING ANILINE AND DERIVATIVES THEREOF | 2010 |
|
RU2433116C1 |
| METHOD OF PRODUCING TERTIARY AMINES | 2012 |
|
RU2499793C1 |
| METHOD OF OBTAINING SECONDARY AMINES | 2013 |
|
RU2523456C1 |
| METHOD OF PRODUCING SATURATED CARBOXYLIC ACIDS | 2013 |
|
RU2529026C1 |
| METHOD FOR PREPARING ARYLCHLOROSULFONYL BENZAMIDES FROM BENZOIC ACIDS | 2006 |
|
RU2298548C1 |
| METHOD OF PRODUCING PRIMARY OR SECONDARY ALCOHOLS | 2013 |
|
RU2519950C1 |
