FIELD: medicine.
SUBSTANCE: invention can be used in obtaining heranostic compositions for hyperthermal treatment and/or diagnostics of tumours by means of magnetic resonance tomography. Method of polyol type for obtaining magnetite nanoparticles includes stage, at which said nanoparticles are formed in solvent -polyol, selected from glycerol or propyleneglycol. Magnetite nanoparticles are obtained from metallic iron and FeIII salts, soluble in said polyol at temperature 130-200°C, in presence of mineral acid as catalyst and water. Water is taken in molar ratio 1.5-5 times more than number of moles of applied FeIII salt.
EFFECT: invention makes it possible to obtain magnetite nanoparticles of uniform size and increase SAR value - specific absorption rate of said particles.
6 cl, 1 dwg, 6 tbl, 8 ex
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Authors
Dates
2015-08-10—Published
2010-12-15—Filed