FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to 3-(heteroarylamino)-1,2,3,4-tetrahydro-9H-carbazole derivatives of formula in which R1 represents hydrogen, (C1-C4)alkyl, (C1-C4)alkoxygroup, haloid, trifluoromethoxygroup or trifluoromethyl, R2 represents hydrogen, (C1-C4)alkyl, (C1-C2)alkoxy(C2-C3)alkyl, (C1-C4)fluoroalkyl or (C3-C6)cycloalkyl(C1-C2)alkyl, and R3 represents a heteroaryl group, which is non-substituted or substituted and to their application as modulators of prostaglandin receptors, in particular, the modulators of prostaglandin D2 receptors in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions, containing the claimed compounds and to methods of obtaining thereof.
EFFECT: obtaining pharmaceutical compositions for the treatment of various prostaglandin-mediated diseases and disorders.
23 cl, 10 tbl, 58 ex
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Authors
Dates
2015-09-10—Published
2011-03-21—Filed