FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine. Device comprises structures mounted on the surface to form nanotopography. A random or ordered structure pattern can be created as a complex pattern comprising structures of different size and/or shape. Microneedles can be effectively used to deliver a preparation to a cell or tissue. The devices can be used to change the cell behaviour either directly, or indirectly by the reaction of the created nanotopography with a cytoplasmic cell membrane and/or an extracellular matrix component.
EFFECT: there are described nanotopography-based methods and devices for the reaction with the component of connective tissue of derma.
20 cl, 48 dwg, 11 tbl
| Title |
Year |
Author |
Number |
| DEVICE FOR DELIVERING DRUG USED IN RHEUMATOID ARTHRITIS |
2011 |
|
RU2585159C2 |
| MEDICAL DEVICES FOR DELIVERY OF SIRNA |
2011 |
|
RU2585138C2 |
| ARRAY OF MICRONEEDLES MANUFACTURED BY INJECTION-COMPRESSION MOULDING AND METHOD OF MOULDING ARRAY OF MICRONEEDLES |
2011 |
|
RU2560646C9 |
| METHOD FOR IMPROVING EPITHELIAL BARRIER PENETRATION |
2011 |
|
RU2574137C2 |
| TRANSDERMAL DELIVERY OF HIGH-BINDED BIOACTIVE AGENTS |
2012 |
|
RU2630610C2 |
| MICRONEEDLE, MOULD FOR PRODUCING SAME AND METHOD OF PRODUCING MICRONEEDLE |
2014 |
|
RU2679107C2 |
| METHODS AND DEVICES FOR DESMOPRESSIN PREPARATION DELIVERY |
2008 |
- Khershkovitts Sam'Juehl
- Fajn Sejmor
|
RU2472539C2 |
| CONDITIONED ENVIRONMENT AND COMPOSITION BASED ON EXTRACELLULAR MATRIX FROM CELLS CULTIVATED IN HYPOXIC CONDITIONS |
2010 |
- Noton, Gejl, K.
- Zejgler, Frenk
- Baumgartner, Mark
- Niki, Kajl
|
RU2631488C2 |
| DEVICE FOR TRANSDERMAL DELIVERY OF ACTIVE MOLECULES, USE OF DEVICE, AND METHODS FOR MANUFACTURING SUCH A DEVICE AND ITS COMPONENTS |
2018 |
- De Stefano, Luca
- Rea, Ilaria
- Dardano, Principia
- Nicolais, Luigi
|
RU2769695C2 |
| MICRONEEDLE ARRAYS AND METHODS FOR PRODUCING AND USING THEM |
2017 |
- Alary, Marc
- Hopson, Peyton
- Liu, Jan-Joo
- Lunde, Erik
- Patel, Bharat
- Morano, Emanuel
|
RU2750904C2 |
